Article
Specific genetic deficiencies of the A and B isoenzymes of monoamine oxidase are characterized by distinct neurochemical and clinical phenotypes.
The Journal of clinical investigation - 15 Feb 1996
Lenders J W, Eisenhofer G, Abeling N G, Berger W, Murphy D L, Konings C H, Wagemakers L M, Kopin I J, Karoum F, van Gennip A H, Brunner H G
Abstract excerpt
Monoamine oxidase (MAO) exists as two isoenzymes and plays a central role in the metabolism of monoamine neurotransmitters. In this study we compared the neurochemical phenotypes of previously described subjects with genetically determined selective lack of MAO-A or a lack of both MAO-A and MAO-B with those of two subjects with a previously described X chromosome microdeletion in whom we now demonstrate selective...
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