Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes.

doi:10.2337/db14-1653

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes.

Diabetes - 1 Jul 2015

Prudente Sabrina, Shah Hetal, Bailetti Diego, Pezzolesi Marcus, Buranasupkajorn Patinut, Mercuri Luana, Mendonca Christine, De Cosmo Salvatore, Niewczas Monika, Trischitta Vincenzo, Doria Alessandro

Abstract excerpt

Single nucleotide polymorphism (SNP) rs10911021 at the glutamate-ammonia ligase (GLUL) locus has been associated with an increased risk of coronary heart disease in individuals with type 2 diabetes. The effect of this SNP on mortality was investigated among 1,242 white subjects with type 2 diabetes from the Joslin Kidney Study (JKS) (n = 416) and the Gargano Mortality Study (GMS) (n = 826). During a mean...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cause of Death

Share to Diabetes Mellitus, Type 2

Share to Diabetes Treatment and Management

Share to Genetic Associations and Epidemiology

Share to Glutamate-Ammonia Ligase

Share to Helicobacter pylori-related gastroenterology studies

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 25677913
DOI: 10.2337/db14-1653
PMCID: PMC4477355

Genes

GLUL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes.PMID 25677913Read ↗

Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes.Semantic proximity Read ↗

Low-frequency variants in genes involved in glutamic acid metabolism and γ-glutamyl cycle and risk of coronary artery disease in type 2 diabetes.Semantic proximity Read ↗

Genetic variants in glutamate cysteine ligase confer protection against type 2 diabetes.Semantic proximity Read ↗

Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids.Semantic proximity Read ↗

The SNP rs10911021 is associated with oxidative stress in coronary heart disease patients from Pakistan.Semantic proximity Read ↗

ACE genotype, phenotype and all-cause mortality in different cohorts of patients with type 1 diabetes.Semantic proximity Read ↗

Association of GCLM -588C/T and GCLC -129T/C Promoter Polymorphisms of Genes Coding the Subunits of Glutamate Cysteine Ligase with Ischemic Heart Disease Development in Kazakhstan Population.Semantic proximity Read ↗

Associations of MALAT1 rs619586/rs3200401 and ANRIL rs10965215/rs10738605 polymorphisms with type 2 diabetes and diabetic nephropathy risk in an Egyptian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.