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Article

Associations of MALAT1 rs619586/rs3200401 and ANRIL rs10965215/rs10738605 polymorphisms with type 2 diabetes and diabetic nephropathy risk in an Egyptian population.

Frontiers in endocrinology - 1 Jan 2026

Ali Marwa A, Abdealeem Omayma O, Shaker Olfat G, Algammal Mahmoud G, Hemeda Nada F, Ali Doaa Y, Makloph Mohammed, Mohamed Mohamed M, Elebiary Ahmed Magdy, Saleh Asmaa, Kamal Marwa, Mohamed Noura Mostafa, El-Masry Thanaa A

Abstract excerpt

Background: Diabetic nephropathy (DN) is a serious microvascular complication of type 2 diabetes mellitus (T2DM).Single-nucleotide polymorphisms (SNPs) in long non-coding RNAs MALAT1 and ANRIL may influence their expression and function, potentially affecting T2DM and DN risk. Objective: To investigate the association of MALAT1 SNPs rs619586 and rs3200401 and ANRIL SNPs rs10965215 and rs10738605 with T2DM and/or...

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Topics

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Case-Control Studies
Diabetes Mellitus, Type 2
Diabetic Nephropathies
Egypt
Gene Frequency
Polymorphism, Single Nucleotide
Risk Factors
RNA, Long Noncoding

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Identifiers

PMID: 42428670
DOI: 10.3389/fendo.2026.1802490
PMCID: PMC13346653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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