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Article

Rab11a regulates Syntaxin 3 localization and microvillus assembly in enterocytes

1 Jan 2015

Abstract excerpt

Rab11a is a key component of the apical recycling endosome that aids in the trafficking of proteins to the luminal surface in polarized epithelial cells. Utilizing conditional Rab11a-knockout specific to intestinal epithelial cells, and human colonic epithelial CaCo2-BBE cells with stable Rab11a knockdown, we examined the molecular and pathological impact of Rab11a deficiency on the establishment of apical cell...

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PMID: 25673875
DOI: 10.1242/jcs.163303

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