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The Glycosylation Status of PrP <sup>C</sup> Is a Key Factor in Determining Transmissible Spongiform Encephalopathy Transmission between Species

12 Feb 2015

Abstract excerpt

UNLABELLED: The risk of transmission of transmissible spongiform encephalopathies (TSE) between different species has been notoriously unpredictable because the mechanisms of transmission are not fully understood. A transmission barrier between species often prevents infection of a new host with a TSE agent. Nonetheless, some TSE agents are able to cross this barrier and infect new species, with devastating...

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PMID: 25673720
DOI: 10.1128/jvi.02296-14

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