Article
[New approach for JC virus detection and its application for PML diagnosis].
Rinsho shinkeigaku = Clinical neurology - 1 Jan 2014
Nakamichi Kazuo, Lim Chang-Kweng, Saijo Masayuki
Abstract excerpt
Progressive multifocal leukoencephalopathy (PML) is a rare but fatal demyelinating disease of the central nervous system (CNS) caused by JC virus (JCV). The current diagnostic standard for PML is real-time PCR testing of extracted DNA for assessing the presence of JCV DNA in cerebrospinal fluid (CSF). However, because of its sensitivity, real-time PCR assay for JCV testing has a risk of false-positive results due...
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