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Article

Molecular, genetic, and cellular bases for treating eosinophilic esophagitis.

Gastroenterology - 1 May 2015

Rothenberg Marc E

Abstract excerpt

Eosinophilic esophagitis (EoE) was historically distinguished from gastroesophageal reflux disease on the basis of histology and lack of responsiveness to acid suppressive therapy, but it is now appreciated that esophageal eosinophilia can respond to proton pump inhibitors. Genetic and environmental factors contribute to risk for EoE, particularly early-life events. Disease pathogenesis involves activation of...

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Identifiers

PMID: 25666870
DOI: 10.1053/j.gastro.2015.02.002
PMCID: PMC4409569

Genes

CAPN14
CCL26
TSLP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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