Article
Unravelling the pathogenesis of Eosinophilic Esophagitis from genetic predisposition to environmental triggers.
Clinical and experimental immunology - 21 Jan 2025
Aziz Sohail, Pellegrino Raffaele, Buono Pietro, Creoli Mara, Torre Diego, Chiantese Claudia, Colucci Antonio, Casertano Marianna, Ciamarra Paola, Federico Alessandro, Gravina Antonietta Gerarda, Strisciuglio Caterina
Abstract excerpt
Eosinophilic Esophagitis (EoE) is a chronic disease primarily driven by immune-mediated pathogenesis, characterized by eosinophil-driven inflammation of the oesophagus, leading to organ dysfunction and fibrosis. Although initially considered a rare disorder, EoE is now recognized as one of the leading causes of food impaction and dysphagia. Advances in knowledge and diagnostic techniques have contributed to its...
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