Dynamic tuning of lymphocytes: physiological basis, mechanisms, and function.

Abstract excerpt

Dynamic tuning of cellular responsiveness as a result of repeated stimuli improves the ability of cells to distinguish physiologically meaningful signals from each other and from noise. In particular, lymphocyte activation thresholds are subject to tuning, which contributes to maintaining tolerance to self-antigens and persisting foreign antigens, averting autoimmunity and immune pathogenesis, but allowing...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Survival
• Share to Homeostasis
• Share to Immunologic Memory