Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KRAS and BRAF gene mutations and DNA mismatch repair status in Chinese colorectal carcinoma patients.

World journal of gastroenterology - 7 Feb 2015

Ye Ju-Xiang, Liu Yan, Qin Yun, Zhong Hao-Hao, Yi Wei-Ning, Shi Xue-Ying

Abstract excerpt

AIM: To investigate gene mutations and DNA mismatch repair (MMR) protein abnormality in Chinese colorectal carcinoma (CRC) patients and their correlations with clinicopathologic features. METHODS: Clinical and pathological information for 535 patients including 538 tumors was reviewed and recorded. Mutation analyses for exon 2 of KRAS gene and exon 15 of BRAF gene were performed by Sanger sequencing except that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Asian People
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Differentiation

Share to DNA Mutational Analysis

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to Immunohistochemistry

Source

Open in PubMed Open full text

Identifiers

PMID: 25663779
DOI: 10.3748/wjg.v21.i5.1595
PMCID: PMC4316102

Genes

BRAF
KRAS
MLH1
PMS2
MSH2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KRAS and BRAF gene mutations and DNA mismatch repair status in Chinese colorectal carcinoma patients.PMID 25663779Read ↗

Comprehensive analysis of gene mutations and mismatch repair in Chinese colorectal cancer patientsSemantic proximity Read ↗

Distinct Clinicopathological Patterns of Mismatch Repair Status in Colorectal Cancer Stratified by KRAS Mutations.Semantic proximity Read ↗

Patterns and characteristics of mismatch repair deficiency colorectal cancer from central ChinaSemantic proximity Read ↗

Clinic-pathological characteristics of MMR protein, KRAS-NRAS-BRAF gene mutation, HER-2 and PD-L1 status in 3822 Chinese colorectal cancer patientsSemantic proximity Read ↗

KRAS/NRAS/BRAF Mutations and Mismatch Repair Deficiency in Patients with Early-Onset Colorectal Cancer: A Clinicopathological Analysis.Semantic proximity Read ↗

Genetic landscape of Chinese colorectal cancer: insights into germline and somatic mutations.Semantic proximity Read ↗

Mismatch Repair Deficiency in Colorectal Adenocarcinoma: Clinical, Pathological and Prognostic Features, a Single Center’s Experience of 1002 CasesSemantic proximity Read ↗

[Difference analysis of somatic mutations between deficient mismatch repair and proficient mismatch repair gene related with colorectal cancer].Semantic proximity Read ↗

Prevalence and clinicopathologic/molecular characteristics of mismatch repair-deficient colorectal cancer in the under-50-year-old Japanese population.Semantic proximity Read ↗

Characteristics of colorectal carcinoma patients with PMS2 defects detected by immunohistochemistrySemantic proximity Read ↗

Mutation analysis of 13 driver genes of colorectal cancer-related pathways in Taiwanese patients.Semantic proximity Read ↗

Both MLH1 deficiency and BRAFV600E mutation are a unique characteristic of colorectal medullary carcinoma: An observational study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.