Article
KRAS and BRAF gene mutations and DNA mismatch repair status in Chinese colorectal carcinoma patients.
World journal of gastroenterology - 7 Feb 2015
Ye Ju-Xiang, Liu Yan, Qin Yun, Zhong Hao-Hao, Yi Wei-Ning, Shi Xue-Ying
Abstract excerpt
AIM: To investigate gene mutations and DNA mismatch repair (MMR) protein abnormality in Chinese colorectal carcinoma (CRC) patients and their correlations with clinicopathologic features. METHODS: Clinical and pathological information for 535 patients including 538 tumors was reviewed and recorde...
Topics
- Adaptor Proteins, Signal Transducing
- Adenocarcinoma
- Aged
- Asian People
- Base Sequence
- Biomarkers, Tumor
- Cell Differentiation
- China
- Colorectal Neoplasms
- DNA Mismatch Repair
- DNA Mutational Analysis
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Immunohistochemistry
- Male
- Microsatellite Instability