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Article

Application of molecular profiling in clinical trials for advanced metastatic cancers.

Journal of the National Cancer Institute - 1 Apr 2015

Kummar Shivaani, Williams P Mickey, Lih Chih-Jian, Polley Eric C, Chen Alice P, Rubinstein Larry V, Zhao Yingdong, Simon Richard M, Conley Barbara A, Doroshow James H

Abstract excerpt

There is growing interest in the application of molecular profiling, including sequencing, genotyping, and/or mRNA expression profiling, to the analysis of patient tumors with the objective of applying these data to inform therapeutic choices for patients with advanced cancers. Multiple clinical trials that are attempting to validate this personalized or precision medicine approach are in various stages of...

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Identifiers

PMID: 25663694
DOI: 10.1093/jnci/djv003
PMCID: PMC4334817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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