Article
The clinical trial landscape in oncology and connectivity of somatic mutational profiles to targeted therapies.
Human genomics - 16 Jan 2016
Patterson Sara E, Liu Rangjiao, Statz Cara M, Durkin Daniel, Lakshminarayana Anuradha, Mockus Susan M
Abstract excerpt
BACKGROUND: Precision medicine in oncology relies on rapid associations between patient-specific variations and targeted therapeutic efficacy. Due to the advancement of genomic analysis, a vast literature characterizing cancer-associated molecular aberrations and relative therapeutic relevance has been published. However, data are not uniformly reported or readily available, and accessing relevant information in...
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