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Article

Prognostic impact of polymorphism of matrix metalloproteinase-2 and metalloproteinase tissue inhibitor-2 promoters in breast cancer in Tunisia: case-control study.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2015

Ben Néjima Dalel, Ben Zarkouna Yosr, Gammoudi Amor, Manai Mohamed, Boussen Hamouda

Abstract excerpt

Matrix metalloproteinases (MMPs) are proteolytic enzymes that play important roles in tumor invasion and metastasis by degrading extracellular matrix components. Genetic variations in promoter regions of MMP genes, affecting their expression, have been associated with susceptibility to cancers. The aim of this study was to investigate the susceptibility and prognostic implications of the matrix...

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Identifiers

PMID: 25656607
DOI: 10.1007/s13277-014-3023-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Prognostic impact of polymorphism of matrix metalloproteinase-2 and metalloproteinase tissue inhibitor-2 promoters in breast cancer in Tunisia: case-control study.PMID 25656607Read ↗

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