Article
Comprehensive mutation profiling by next-generation sequencing of effusion fluids from patients with high-grade serous ovarian carcinoma.
Cancer cytopathology - 1 May 2015
Shah Ronak H, Scott Sasinya N, Brannon A Rose, Levine Douglas A, Lin Oscar, Berger Michael F
Abstract excerpt
BACKGROUND: Mutation analysis for personalized treatment has become increasingly important in the management of different types of cancer. The advent of new DNA extraction protocols and sequencing platforms with reduced DNA input requirements might allow the use of cytology specimens for high-throughput mutation analysis. In this study, the authors evaluated the use of effusion fluid for next-generation...
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