Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive insights into transcriptional adaptation of intracellular mycobacteria by microbe-enriched dual RNA sequencing

4 Feb 2015

Abstract excerpt

BACKGROUND: The human pathogen Mycobacterium tuberculosis has the capacity to escape eradication by professional phagocytes. During infection, M. tuberculosis resists the harsh environment of phagosomes and actively manipulates macrophages and dendritic cells to ensure prolonged intracellular survival. In contrast to other intracellular pathogens, it has remained difficult to capture the transcriptome of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune responses and vaccinations
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25649146
DOI: 10.1186/s12864-014-1197-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive insights into transcriptional adaptation of intracellular mycobacteria by microbe-enriched dual RNA sequencingPMID 25649146Read ↗

Comparative transcriptomics reveals common and strain-specific responses of human macrophages to infection with Mycobacterium tuberculosis and Mycobacterium bovis BCGSemantic proximity Read ↗

Targeted RNA-Seq Reveals the M. tuberculosis Transcriptome from an In Vivo Infection ModelSemantic proximity Read ↗

Dual RNA Sequencing of Mycobacterium tuberculosis-Infected Human Splenic Macrophages Reveals a Strain-Dependent Host–Pathogen Response to InfectionSemantic proximity Read ↗

Transcriptomic characterization of tuberculous sputum reveals a host Warburg effect and microbial cholesterol catabolismSemantic proximity Read ↗

Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targetsSemantic proximity Read ↗

Comparative 'omics analyses differentiate Mycobacterium tuberculosis and Mycobacterium bovis and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilliSemantic proximity Read ↗

Integrative Analysis of Human Macrophage Inflammatory Response Related to Mycobacterium tuberculosis VirulenceSemantic proximity Read ↗

Transcriptome analysis of mycobacteria in sputum samples of pulmonary tuberculosis patientsSemantic proximity Read ↗

Illuminating host-mycobacterial interactions with functional genomic screening to inhibit mycobacterial pathogenesisSemantic proximity Read ↗

Comparative ‘omics analyses differentiate <i>Mycobacterium tuberculosis</i> and <i>Mycobacterium bovis</i> and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilliSemantic proximity Read ↗

Incomplete transcripts dominate the <i>Mycobacterium tuberculosis</i> transcriptomeSemantic proximity Read ↗

Integrative and comparative genomic analyses of mammalian macrophage responses to intracellular mycobacterial pathogensSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.