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Transcriptome analysis of mycobacteria in sputum samples of pulmonary tuberculosis patients

10 Mar 2017

Abstract excerpt

Pulmonary tuberculosis, the disease caused by Mycobacterium tuberculosis, still retains a top rank among the deadliest communicable diseases. Sputum expectorated during the disease continues to be a primary diagnostic specimen and also serves as a reservoir of bacteria. The expression pattern of mycobacteria in sputum will lead to an insight into bacterial adaptation at the most highly transmissible stage of...

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PMID: 28282458
DOI: 10.1371/journal.pone.0173508

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