Article
Proliferation following tetraploidization regulates the size and number of erythrocytes in the blood flow during medaka development, as revealed by the abnormal karyotype of erythrocytes in the medaka TFDP1 mutant.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 May 2015
Taimatsu Kiyohito, Takubo Keiyo, Maruyama Kouichi, Suda Toshio, Kudo Akira
Abstract excerpt
BACKGROUND: For the delivery of oxygen, the correct size/number of erythrocytes is required for proper blood flow. RESULTS: By combined analyses of wild-type (WT) medaka and the kyoho (kyo) mutant, we found proliferation-mediated adaptation for size/number of erythrocytes in the blood flow during medaka development. Before the start of heart beating in the WT medaka, the karyotype of erythrocytes was 2N-4N. After...
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