Article
Characterization of mutations affecting embryonic hematopoiesis in the medaka, Oryzias latipes.
Mechanisms of development - 1 Jul 2004
Tanaka Kimiko, Ohisa Satoshi, Orihara Nobuaki, Sakaguchi Sae, Horie Kyohei, Hibiya Kenta, Konno Sayaka, Miyake Akimitsu, Setiamarga Davin, Takeda Hiroyuki, Imai Yoshiyuki, Kudo Akira
Abstract excerpt
In a genetic screen for mutations affecting organogenesis in the medaka, Oryzias latipes, we identified eight mutants with defects in embryonic hematopoiesis. These mutations were classified into seven complementation groups. In this paper, we characterize the five mutants that were confirmed in the next generation. The beni fuji mutant was defective in the generation of blood cells, exhibiting reduced blood...
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