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Article

Oct-3/4 modulates the drug-resistant phenotype of glioblastoma cells through expression of ATP binding cassette transporter G2.

Biochimica et biophysica acta - 1 Jun 2015

Hosokawa Yuki, Takahashi Hisaaki, Inoue Akihiro, Kawabe Yuya, Funahashi Yu, Kameda Kenji, Sugimoto Kana, Yano Hajime, Harada Hironobu, Kohno Shohei, Ohue Shiro, Ohnishi Takanori, Tanaka Junya

Abstract excerpt

BACKGROUND: Drug resistance is a major obstacle for the efficacy of chemotherapeutic treatment of tumors. Oct-3/4, a self-renewal regulator in stem cells, is expressed in various kinds of solid tumors including glioblastoma. Although Oct-3/4 expression has been implicated in the malignancy and pr...

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Share to Antimetabolites, Antineoplastic
Share to ATP Binding Cassette Transporter, Subfamily G, Member 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25644290
DOI: 10.1016/j.bbagen.2015.01.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25644290-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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