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Article

The Phenomenon of Multidrug Resistance in Glioblastomas

16 Jun 2021

Abstract excerpt

The most common and aggressive brain tumor in the adult population is glioblastoma (GBM). The lifespan of patients does not exceed 22 months. One of the reasons for the low effectiveness of GBM treatment is its radioresistance and chemoresistance. In the current review, we discuss the phenomenon of multidrug resistance of GBM in the context of the expression of ABC family transporter proteins and the mechanisms...

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PMID: 34216549
DOI: 10.1016/j.hemonc.2021.05.006

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