Molecular typing of isolates of Rickettsia rickettsii by use of DNA sequencing of variable intergenic regions.

doi:10.1128/JCM.00367-07

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Article

Molecular typing of isolates of Rickettsia rickettsii by use of DNA sequencing of variable intergenic regions.

Journal of clinical microbiology - 1 Aug 2007

Karpathy Sandor E, Dasch Gregory A, Eremeeva Marina E

Abstract excerpt

Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever, is found throughout the Americas, where it is associated with different animal reservoirs and tick vectors. No molecular typing system currently exists to allow for the robust differentiation of isolates of R. rickettsii. Analysis of eight completed genome sequences of rickettsial species revealed a high degree of sequence conservation...

Topics

Animals
Bacterial Typing Techniques
Cluster Analysis
DNA, Bacterial
DNA, Intergenic
Genotype
Humans
Molecular Sequence Data
Phylogeny
Polymorphism, Genetic
Rickettsia rickettsii
Rocky Mountain Spotted Fever
Sequence Analysis, DNA
Ticks

Source

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Identifiers

PMID: 17553977
DOI: 10.1128/JCM.00367-07
PMCID: PMC1951237

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