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Article

A survival Kit for pancreatic beta cells: stem cell factor and c-Kit receptor tyrosine kinase.

Diabetologia - 1 Apr 2015

Feng Zhi-Chao, Riopel Matthew, Popell Alex, Wang Rennian

Abstract excerpt

The interactions between c-Kit and its ligand, stem cell factor (SCF), play an important role in haematopoiesis, pigmentation and gametogenesis. c-Kit is also found in the pancreas, and recent studies have revealed that c-Kit marks a subpopulation of highly proliferative pancreatic endocrine cells that may harbour islet precursors. c-Kit governs and maintains pancreatic endocrine cell maturation and function via...

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Source

Identifiers

PMID: 25643653
DOI: 10.1007/s00125-015-3504-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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