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Article

The SCF/c-KIT system in the male: Survival strategies in fertility and cancer

30 Oct 2014

Abstract excerpt

Maintaining the delicate balance between cell survival and death is of the utmost importance for the proper development of germ cells and subsequent fertility. On the other hand, the fine regulation of tissue homeostasis by mechanisms that control cell fate is a factor that can prevent carcinogenesis. c-KIT is a type III receptor tyrosine kinase activated by its ligand, stem cell factor (SCF). c-KIT signaling...

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PMID: 25359157
DOI: 10.1002/mrd.22430

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