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Article

Gene expression in transformed lymphocytes reveals variation in endomembrane and HLA pathways modifying cystic fibrosis pulmonary phenotypes.

American journal of human genetics - 5 Feb 2015

O'Neal Wanda K, Gallins Paul, Pace Rhonda G, Dang Hong, Wolf Whitney E, Jones Lisa C, Guo XueLiang, Zhou Yi-Hui, Madar Vered, Huang Jinyan, Liang Liming, Moffatt Miriam F, Cutting Garry R, Drumm Mitchell L, Rommens Johanna M, Strug Lisa J, Sun Wei, Stonebraker Jaclyn R, Wright Fred A, Knowles Michael R

Abstract excerpt

Variation in cystic fibrosis (CF) phenotypes, including lung disease severity, age of onset of persistent Pseudomonas aeruginosa (P. aeruginosa) lung infection, and presence of meconium ileus (MI), has been partially explained by genome-wide association studies (GWASs). It is not expected that GW...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25640674
DOI: 10.1016/j.ajhg.2014.12.022
PMCID: PMC4320265

Genes

LPAR6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25640674-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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