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Article

Differentially expressed genes associated with disease severity in siblings with cystic fibrosis.

Pediatric pulmonology - 1 May 2021

Ekinci İlksen Berfin, Hızal Mina, Emiralioğlu Nagehan, Özçelik Uğur, Yalçın Ebru, Doğru Deniz, Kiper Nural, Dayangaç-Erden Didem

Abstract excerpt

Cystic fibrosis (CF) is an autosomal recessive disease caused by CFTR gene mutations. Despite having the same mutation, CF patients may demonstrate clinical variability in severity and prognosis of the disease. In this study, we aimed to determine differentially expressed genes between mild and severe siblings with same genotype. We performed targeted real-time polymerase chain reaction based transcriptomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33369261
DOI: 10.1002/ppul.25237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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