Article
Polymorphisms in alcohol and tobacco metabolism genes in head and neck cancer in the Basque Country.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Nov 2015
Bediaga Naiara G, Marichalar-Mendia Xabier, Rey-Barja Natalia, Setien-Olarra Amaia, Gonzalez-Garcia José A, de Pancorbo Marian Martinez, Aguirre-Urizar José M, Acha-Sagredo Amelia
Abstract excerpt
BACKGROUND: The Basque Country has one of the highest rates of head and neck squamous cell carcinoma (HNSCC) in Europe, although tobacco and alcohol consumption are not high when compared to other European countries where HNSCC incidence is lower. Our aim was to determine the role of genetic variation with regard to the metabolism of alcohol and carcinogens from tobacco smoke in the Basque Country. METHODS:...
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