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Article

Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells.

PloS one - 1 Jan 2015

Furukawa Masashi, Wheeler Sarah, Clark Amanda M, Wells Alan

Abstract excerpt

PURPOSE: The lung is one of the most common sites of breast cancer metastasis. While metastatic seeding is often accompanied by a dormancy-promoting mesenchymal to epithelial reverting transitions (MErT), we aimed to determine whether lung epithelial cells can impart this phenotype on aggressive breast cancer cells. METHODS: Co-culture experiments of normal lung epithelial cell lines (SAEC, NHBE or BEAS-2B) and...

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Identifiers

PMID: 25635394
DOI: 10.1371/journal.pone.0118060
PMCID: PMC4311980

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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