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Article

Benign mammary epithelial cells enhance the transformed phenotype of human breast cancer cells.

BMC cancer - 16 Jul 2010

Poczobutt Joanna M, Tentler John, Lu Xian, Schedin Pepper J, Gutierrez-Hartmann Arthur

Abstract excerpt

BACKGROUND: Recent research has yielded a wealth of data underscoring the key role of the cancer microenvironment, especially immune and stromal cells, in the progression of cancer and the development of metastases. However, the role of adjacent benign epithelial cells, which provide initial cell-cell contacts with cancer cells, in tumor progression has not been thoroughly examined. In this report we addressed...

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Identifiers

PMID: 20637104
DOI: 10.1186/1471-2407-10-373
PMCID: PMC2913961

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