Article
Sequence-specific cleavage of dsRNA by Mini-III RNase.
Nucleic acids research - 11 Mar 2015
Głów Dawid, Pianka Dariusz, Sulej Agata A, Kozłowski Łukasz P, Czarnecka Justyna, Chojnowski Grzegorz, Skowronek Krzysztof J, Bujnicki Janusz M
Abstract excerpt
Ribonucleases (RNases) play a critical role in RNA processing and degradation by hydrolyzing phosphodiester bonds (exo- or endonucleolytically). Many RNases that cut RNA internally exhibit substrate specificity, but their target sites are usually limited to one or a few specific nucleotides in single-stranded RNA and often in a context of a particular three-dimensional structure of the substrate. Thus far, no...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.