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Article

Mouse ATP-Binding Cassette (ABC) Transporters Conferring Multi-Drug Resistance

28 Apr 2015

Abstract excerpt

The ABC (ATP-binding cassette) transporter is one of the largest and most ancient protein families with members functioning from protozoa to human. The resistance of cancer and tumor cells to anticancer drugs is due to the over-expression of some ABC transporters, which may finally lead to chemotherapy failure. The mouse ABC transporters are classified into seven subfamilies by phylogenetic analysis. The mouse...

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PMID: 25634448
DOI: 10.2174/1871520615666150129212723

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