Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity

29 Jan 2015

Abstract excerpt

Developing tissues contain motile populations of cells that can self-organize into spatially ordered tissues based on differences in their interfacial surface energies. However, it is unclear how self-organization by this mechanism remains robust when interfacial energies become heterogeneous in either time or space. The ducts and acini of the human mammary gland are prototypical heterogeneous and dynamic tissues...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3D Printing in Biomedical Research
Share to Cancer Cells and Metastasis
Share to Cellular Mechanics and Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25633040
DOI: 10.1073/pnas.1410776112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticityPMID 25633040Read ↗

Self-organization is a dynamic and lineage-intrinsic property of mammary epithelial cellsSemantic proximity Read ↗

A mechanism for epithelial-mesenchymal heterogeneity in a population of cancer cellsSemantic proximity Read ↗

Topography of epithelial-mesenchymal plasticity.Semantic proximity Read ↗

The epithelial-mesenchymal plasticity landscape: principles of design and mechanisms of regulation.Semantic proximity Read ↗

Heterotypic interfacial tension between oncogenic and wild-type populations forms the mechanical basis of tissue-specific oncogenesis in epitheliaSemantic proximity Read ↗

Heterotypic interfacial tension between oncogenic and wild-type populations forms the mechanical basis of tissue-specific oncogenesis in epithelia.Semantic proximity Read ↗

“Patchiness” in Mechanical Stiffness across a Tumor as an Early-Stage Marker for MalignancySemantic proximity Read ↗

Self-organization in cancer: Implications for histopathology, cancer cell biology, and metastasisSemantic proximity Read ↗

Bridging the Gap in Cancer Cell Behavior Against Matrix Stiffening: Insights from a Trizonal ModelSemantic proximity Read ↗

Coherent angular motion in the establishment of multicellular architecture of glandular tissuesSemantic proximity Read ↗

Oncogenic RAS instructs morphological transformation of human epithelia via differential tissue mechanicsSemantic proximity Read ↗

Extracellular domains of E-cadherin determine key mechanical phenotypes of an epithelium through cell- and non-cell-autonomous outside-in signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.