Article
Population-specific association of genes for telomere-associated proteins with longevity in an Italian population.
Biogerontology - 1 Jun 2015
Crocco Paolina, Barale Roberto, Rose Giuseppina, Rizzato Cosmeri, Santoro Aurelia, De Rango Francesco, Carrai Maura, Fogar Paola, Monti Daniela, Biondi Fiammetta, Bucci Laura, Ostan Rita, Tallaro Federica, Montesanto Alberto, Zambon Carlo-Federico, Franceschi Claudio, Canzian Federico, Passarino Giuseppe, Campa Daniele
Abstract excerpt
Leukocyte telomere length (LTL) has been observed to be hereditable and correlated with longevity. However, contrasting results have been reported in different populations on the value of LTL heritability and on how biology of telomeres influences longevity. We investigated whether the variability of genes correlated to telomere maintenance is associated with telomere length and affects longevity in a population...
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