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Article

The functional VNTR MNS16A of the TERT gene is associated with human longevity in a population of Central Italy.

Experimental gerontology - 1 Jun 2013

Concetti Fabio, Lucarini Nazzareno, Carpi Francesco M, Di Pietro Fabio, Dato Serena, Capitani Melania, Nabissi Massimo, Santoni Giorgio, Mignini Fiorenzo, Passarino Giuseppe, Napolioni Valerio

Abstract excerpt

BACKGROUND: Telomerase, encoded by TERT, is the ribonucleoprotein polymerase that maintains telomere ends and it plays a crucial role in cellular senescence. TERT single nucleotide polymorphisms (SNPs) have been associated both with various malignancies and telomere length (TL). The association of TERT SNPs with longevity remains uncertain and varies with ethnicity. The aim of this study was to investigate...

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Identifiers

PMID: 23562826
DOI: 10.1016/j.exger.2013.03.009

Genes

TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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