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Article

Worldwide genetic structure in 37 genes important in telomere biology.

Heredity - 1 Feb 2012

Mirabello L, Yeager M, Chowdhury S, Qi L, Deng X, Wang Z, Hutchinson A, Savage S A

Abstract excerpt

Telomeres form the ends of eukaryotic chromosomes and are vital in maintaining genetic integrity. Telomere dysfunction is associated with cancer and several chronic diseases. Patterns of genetic variation across individuals can provide keys to further understanding the evolutionary history of genes. We investigated patterns of differentiation and population structure of 37 telomere maintenance genes among 53...

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Identifiers

PMID: 21731055
DOI: 10.1038/hdy.2011.55
PMCID: PMC3193882

Genes

ACD
FST
POT1
TERT
TNKS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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