Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Avian-Origin PB1 Gene Segment Facilitated Replication and Transmissibility of the H3N2/1968 Pandemic Influenza Virus

29 Jan 2015

Abstract excerpt

UNLABELLED: The H2N2/1957 and H3N2/1968 pandemic influenza viruses emerged via the exchange of genomic RNA segments between human and avian viruses. The avian hemagglutinin (HA) allowed the hybrid viruses to escape preexisting immunity in the human population. Both pandemic viruses further received the PB1 gene segment from the avian parent (Y. Kawaoka, S. Krauss, and R. G. Webster, J Virol 63:4603-4608, 1989),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Disease Management and Epidemiology
Share to Influenza Virus Research Studies
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25631088
DOI: 10.1128/jvi.03194-14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Avian-Origin PB1 Gene Segment Facilitated Replication and Transmissibility of the H3N2/1968 Pandemic Influenza VirusPMID 25631088Read ↗

Acquisition of Avian-Origin PB1 Facilitates Viral RNA Synthesis by the 2009 Pandemic H1N1 Virus Polymerase.Semantic proximity Read ↗

The PB1 gene from H9N2 avian influenza virus showed high compatibility and increased mutation rate after reassorting with a human H1N1 influenza virusSemantic proximity Read ↗

The PB1 Gene from H9N2 Avian Influenza Virus Showed High Compatibility and Increased Mutation Rate after Reassorting with a Human H1N1 Influenza VirusSemantic proximity Read ↗

Genetic incompatibilities and reduced transmission in chickens may limit the evolution of reassortants between H9N2 and panzootic H5N8 clade 2.3.4.4 avian influenza virus showing high virulence for mammalsSemantic proximity Read ↗

Increased Pathogenicity of a Reassortant 2009 Pandemic H1N1 Influenza Virus Containing an H5N1 HemagglutininSemantic proximity Read ↗

Full factorial analysis of mammalian and avian influenza polymerase subunits suggests a role of an efficient polymerase for virus adaptation.Semantic proximity Read ↗

Reassortment and mutation of the avian influenza virus polymerase PA subunit overcome species barriers.Semantic proximity Read ↗

Avian influenza virus h3 hemagglutinin may enable high fitness of novel human virus reassortants.Semantic proximity Read ↗

Host origin is a determinant of parallel evolution between influenza virus gene segmentsSemantic proximity Read ↗

Reassortment between avian H5N1 and human H3N2 influenza viruses creates hybrid viruses with substantial virulenceSemantic proximity Read ↗

Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air.Semantic proximity Read ↗

Genetic analysis of the compatibility between polymerase proteins from human and avian strains of influenza A virusesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.