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Article

Full factorial analysis of mammalian and avian influenza polymerase subunits suggests a role of an efficient polymerase for virus adaptation.

PloS one - 21 May 2009

Li Olive T W, Chan Michael C W, Leung Cynthia S W, Chan Renee W Y, Guan Yi, Nicholls John M, Poon Leo L M

Abstract excerpt

Amongst all the internal gene segments (PB2. PB1, PA, NP, M and NS), the avian PB1 segment is the only one which was reassorted into the human H2N2 and H3N2 pandemic strains. This suggests that the reassortment of polymerase subunit genes between mammalian and avian influenza viruses might play r...

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Identifiers

PMID: 19462010
DOI: 10.1371/journal.pone.0005658
PMCID: PMC2680953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19462010-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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