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Article

Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice

15 Sept 2018

Abstract excerpt

OBJECTIVE: Imprinted genes are crucial for the growth and development of fetal and juvenile mammals. Altered imprinted gene dosage causes a variety of human disorders, with growth and development during these crucial early stages strongly linked with future metabolic health in adulthood. Neuronatin (Nnat) is a paternally expressed imprinted gene found in neuroendocrine systems and white adipose tissue and is...

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PMID: 30279096
DOI: 10.1016/j.molmet.2018.09.001

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