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Article

TBX20 loss-of-function mutation contributes to double outlet right ventricle.

International journal of molecular medicine - 1 Apr 2015

Pan Yun, Geng Rui, Zhou Ning, Zheng Gui-Fen, Zhao Hong, Wang Juan, Zhao Cui-Mei, Qiu Xing-Biao, Yang Yi-Qing, Liu Xing-Yuan

Abstract excerpt

Congenital heart disease (CHD), the most prevalent birth defect in humans worldwide, is still a leading non‑infectious cause of infant morbidity and mortality. Increasing evidence demonstrates that genetic risk factors play a key role in the pathogenesis of CHD, and more than 50 genes have been linked to various types of CHD. Nevertheless, CHD is a heterogeneous disorder and the genetic components underpinning...

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Source

Identifiers

PMID: 25625280
DOI: 10.3892/ijmm.2015.2077

Genes

TBX20

Variants

Provenance

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