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Article

A novel TBX5 loss-of-function mutation associated with sporadic dilated cardiomyopathy.

International journal of molecular medicine - 1 Jul 2015

Zhou Wei, Zhao Lan, Jiang Jin-Qi, Jiang Wei-Feng, Yang Yi-Qing, Qiu Xing-Biao

Abstract excerpt

Dilated cardiomyopathy (DCM) represents the most prevalent form of primary cardiomyopathy, and is the most common reason for heart transplantation and a major cause of congestive heart failure. Aggregating evidence demonstrates that genetic defects are associated with DCM, and a great number of mutations in >50 genes have been linked to DCM. However, DCM is a genetically heterogeneous disorder and the genetic...

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Topics

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Share to Atrial Natriuretic Factor
Share to Cardiomyopathy, Dilated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GATA4 Transcription Factor

Share to Mutation, Missense

Share to Sequence Alignment

Share to T-Box Domain Proteins

Share to Transcription, Genetic

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Source

Identifiers

PMID: 25963046
DOI: 10.3892/ijmm.2015.2206

Genes

TBX5
GATA4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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