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Article

The Role of TBX20 Gene Mutations in the Pathogenesis of Congenital Heart Disease: Functional Analysis and Genetic Association Study.

Cardiology - 1 Jan 2025

Liu Caixia, Sun Qi, Li Qing, Qin Zhenzhen, Wen Yunhong, Liu Caixia

Abstract excerpt

INTRODUCTION: Congenital heart disease (CHD) is a common congenital anomaly with a significant global health impact, but its genetic underpinnings remain partially understood. TBX20 gene mutations have been implicated in CHD pathogenesis, with effects on cardiac development and function. This study investigates the impact of TBX20 mutations on CHD risk through a combination of experimental analysis and...

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Source

Identifiers

PMID: 39681102
DOI: 10.1159/000542803

Genes

TBX20

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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