Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polygenic determinants of Parkinson's disease in a Chinese population.

Neurobiology of aging - 1 Apr 2015

Guo Ji-Feng, Li Kai, Yu Ri-Li, Sun Qi-Yin, Wang Lei, Yao Ling-Yan, Hu Ya-Cen, Lv Zhan-Yun, Luo Lin-Zi, Shen Lu, Jiang Hong, Yan Xin-Xiang, Pan Qian, Xia Kun, Tang Bei-Sha

Abstract excerpt

It has been reported that some single-nucleotide polymorphisms (SNPs) are associated with the risk of Parkinson's disease (PD), but whether a combination of these SNPs would have a stronger association with PD than any individual SNP is unknown. Sixteen SNPs located in the 8 genes and/or loci (SNCA, LRRK2, MAPT, GBA, HLA-DR, BST1, PARK16, and PARK17) were analyzed in a Chinese cohort consisting of 1061...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADP-ribosyl Cyclase
Share to alpha-Synuclein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, CD

Share to GPI-Linked Proteins

Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Share to Multifactorial Inheritance

Share to Parkinson Disease

Share to Protein Serine-Threonine Kinases

Source

Identifiers

PMID: 25623333
DOI: 10.1016/j.neurobiolaging.2014.12.030

Genes

BST1
SNCA
MAPT

Variants

rs356165
rs356165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polygenic determinants of Parkinson's disease in a Chinese population.PMID 25623333Read ↗

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.Semantic proximity Read ↗

Association analysis and polygenic risk score evaluation of 38 GWAS-identified Loci in a Chinese population with Parkinson's disease.Semantic proximity Read ↗

Association of GWAS loci with PD in China.Semantic proximity Read ↗

Exploring the Effects of Genetic Variants on Clinical Profiles of Parkinson's Disease Assessed by the Unified Parkinson's Disease Rating Scale and the Hoehn-Yahr Stage.Semantic proximity Read ↗

Analysis of genome-wide association study-linked loci in Parkinson's disease of Mainland China.Semantic proximity Read ↗

Association analysis of 15 GWAS-linked loci with Parkinson's disease in Chinese Han population.Semantic proximity Read ↗

SNPs in SNCA, MCCC1, DLG2, GBF1 and MBNL2 are associated with Parkinson's disease in southern Chinese population.Semantic proximity Read ↗

Genome-wide association study reveals genetic risk underlying Parkinson's disease.Semantic proximity Read ↗

An association between the PARK16 locus and Parkinson's disease in a cohort from eastern China.Semantic proximity Read ↗

Association between PARK16 gene polymorphisms and susceptibility of Parkinson's disease in a Chinese population.Semantic proximity Read ↗

Penetrance of LRRK2 G2385R and R1628P is modified by common PD-associated genetic variants.Semantic proximity Read ↗

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.