Article
Association of GWAS loci with PD in China.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2011
Chang Xue-Li, Mao Xue-Ye, Li Hui-Hua, Zhang Jin-Hong, Li Nan-Nan, Burgunder Jean-Marc, Peng Rong, Tan Eng-King
Abstract excerpt
Genome-wide association studies (GWAS) have identified numerous single-nucleotide polymorphisms (SNPs) at four loci (SNCA, PARK16, LRRK2, BST1) that can modulate the risk of Parkinson's disease (PD). The strength of these associations has yet to be clarified in Mainland China. Ethnic specific effect is an important consideration in GWAS analysis. Using a case-control methodology, we genotyped multiple SNPs at...
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