Article
Tumour necrosis factor-α plus interleukin-10 low producer phenotype predicts acute kidney injury and death in intensive care unit patients.
Clinical and experimental immunology - 1 Aug 2013
Dalboni M A, Quinto B M R, Grabulosa C C, Narciso R, Monte J C, Durão M, Rizzo L, Cendoroglo M, Santos O P, Batista M C
Abstract excerpt
Genetic polymorphism studies of cytokines may provide an insight into the understanding of acute kidney injury (AKI) and death in intensive care unit (ICU) patients. The aim of this study was to investigate whether the genetic polymorphisms of -308 G < A tumour necrosis factor (TNF)-α, -174 G > C interleukin (IL)-6 and -1082 G > A IL-10 may predispose ICU patients to the development of AKI and/or death. In a...
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