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Article

Functional histopathological markers of aldosterone producing adenoma and somatic KCNJ5 mutations.

Molecular and cellular endocrinology - 15 Jun 2015

Fernandes-Rosa Fabio Luiz, Amar Laurence, Tissier Frédérique, Bertherat Jérôme, Meatchi Tchao, Zennaro Maria-Christina, Boulkroun Sheerazed

Abstract excerpt

The current pathological diagnosis of Aldosterone Producing Adenoma (APA) is limited to the description of nodules and/or hyperplasia in the resected adrenal gland, independent of their functional characteristics. The aim of our study was to characterize histopathological markers to confirm the presence and identify the sites of aldosterone production and to discriminate KCNJ5-related APA. We investigated 18...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adrenal Gland Neoplasms

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Share to G Protein-Coupled Inwardly-Rectifying Potassium Channels

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Source

Identifiers

PMID: 25617716
DOI: 10.1016/j.mce.2015.01.020

Genes

KCNJ5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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