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Article

Decreased expression of DUSP4 is associated with liver and lung metastases in colorectal cancer.

Medical oncology (Northwood, London, England) - 1 Jan 2013

Saigusa Susumu, Inoue Yasuhiro, Tanaka Koji, Toiyama Yuji, Okugawa Yoshinaga, Shimura Tadanobu, Hiro Junichiro, Uchida Keiichi, Mohri Yasuhiko, Kusunoki Masato

Abstract excerpt

Dual-specificity protein phosphatase 4 (DUSP4), a negative regulator of extracellular-regulated kinase activity, is a potential mediator of resistance to chemotherapy and a tumor suppressor. The aim of this study is to clarify the association between DUSP4 gene expression and clinical outcome in patients with colorectal cancer. Patients who underwent surgery for colorectal cancer were enrolled in this study (n =...

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Share to Dual-Specificity Phosphatases
Share to Genes, Tumor Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intestinal Mucosa

Share to Liver Neoplasms

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Share to Neoplasm Metastasis

Share to Proto-Oncogene Proteins p21(ras)

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Source

Identifiers

PMID: 23749251
DOI: 10.1007/s12032-013-0620-x

Genes

DUSP4
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Decreased expression of DUSP4 is associated with liver and lung metastases in colorectal cancer.PMID 23749251Read ↗

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