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Article

RNA Interference Against Cancer/Testis Genes Identifies Dual Specificity Phosphatase 21 as a Potential Therapeutic Target in Human Hepatocellular Carcinoma

8 Aug 2013

Abstract excerpt

UNLABELLED: Cancer/testis (CT) antigens have been considered therapeutic targets for treating cancers. However, a central question is whether their expression contributes to tumorigenesis or if they are functionally irrelevant by-products derived from the process of cellular transformation. In any case, these CT antigens are essential for cancer cell survival and may serve as potential therapeutic targets....

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PMID: 23929653
DOI: 10.1002/hep.26665

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