Article
Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population.
Journal of translational medicine - 21 Sept 2013
Torres-García Diana, Cruz-Lagunas Alfredo, García-Sancho Figueroa Ma Cecilia, Fernández-Plata Rosario, Baez-Saldaña Renata, Mendoza-Milla Criselda, Barquera Rodrigo, Carrera-Eusebio Aida, Ramírez-Bravo Salomón, Campos Lizeth, Angeles Javier, Vargas-Alarcón Gilberto, Granados Julio, Gopal Radha, Khader Shabaana A, Yunis Edmond J, Zuñiga Joaquin
Abstract excerpt
BACKGROUND: The control of Mycobacterium tuberculosis (Mtb) infection begins with the recognition of mycobacterial structural components by toll like receptors (TLRs) and other pattern recognition receptors. Our objective was to determine the influence of TLRs polymorphisms in the susceptibility to develop tuberculosis (TB) in Amerindian individuals from a rural area of Oaxaca, Mexico with high TB incidence....
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