Article
Toll Like Receptor-4 Gene Polymorphism and Susceptibility to Pulmonary Tuberculosis.
The Egyptian journal of immunology - 1 Jul 2019
Fouad Nehad A, Saeed Amal M, Mahedy Ahmed W
Abstract excerpt
Tuberculosis (TB) affects human life globally for a long time. The difference in clinical outcome of infection suggests that host genetic makeup is responsible for such variability. Toll like receptors (TLRs) are pattern recognition receptors and have a significant role in mycobacterial recognition by the innate immune system. TLR-4 is the key receptor in initiation of innate immunity against M. tuberculosis....
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