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Article

A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis.

Genes and immunity - 1 Jul 2007

Thuong N T T, Hawn T R, Thwaites G E, Chau T T H, Lan N T N, Quy H T, Hieu N T, Aderem A, Hien T T, Farrar J J, Dunstan S J

Abstract excerpt

Tuberculous meningitis (TBM) results from the haematogenous dissemination of Mycobacterium tuberculosis from the lung to the brain. Dissemination is believed to occur early during infection, before the development of adaptive immunity. Toll-like receptor 2 (TLR2) mediates recognition of M. tuberc...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17554342
DOI: 10.1038/sj.gene.6364405

Genes

TLR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17554342-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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