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Article

Supramolecular nanosubstrate-mediated delivery for reprogramming and transdifferentiation of mammalian cells.

Small (Weinheim an der Bergstrasse, Germany) - 3 Jun 2015

Hou Shuang, Choi Jin-sil, Chen Kuan-Ju, Zhang Yang, Peng Jinliang, Garcia Mitch A, Yu Jue-Hua, Thakore-Shah Kaushali, Ro Tracy, Chen Jie-Fu, Peyda Parham, Fan Guoping, Pyle April D, Wang Hao, Tseng Hsian-Rong

Abstract excerpt

Supramolecular nanosubstrate-mediated delivery (SNSMD) leverages the power of molecular self-assembly and a nanostructured substrate platform for the low toxicity, highly efficient co-delivery of biological factors encapsulated in a nanovector. Human fibroblasts are successfully reprogrammed into induced pluripotent stems and transdifferentiated into induced neuronal-like cells.

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Source

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Identifiers

PMID: 25613059
DOI: 10.1002/smll.201402602
PMCID: PMC4961214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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